Genetics

The variants that change how you should be cared for.

Headline variant
CYP2C19
rs4244285 · genotype AG
CPIC

Your body activates clopidogrel less efficiently than most. If cardiology offers clopidogrel, ask about prasugrel or ticagrelor instead.

Intermediate metabolizer: reduced clopidogrel activation. Avoid clopidogrel; consider prasugrel or ticagrelor.

SLCO1B1
rs4149056 · genotype TC
CPIC

Higher risk of muscle pain from statins. Worth asking about your atorvastatin dose or switching to pravastatin.

Reduced function: increased statin-associated myopathy risk. Consider lower-dose atorvastatin or pravastatin.

BRCA1
rs80357906 · genotype AG
USPSTF

Pathogenic variant linked to elevated breast and ovarian cancer risk. With your mother's recent diagnosis, your screening cadence should shift — annual MRI plus mammogram.

Pathogenic variant associated with elevated breast and ovarian cancer risk. Heightened relevance given family history.